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Cat. No.: HY-147665

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hCAIX-IN-7

hCAIX-IN-7 (compound 6c) is a potent and selective hCAIX inhibitor with K_Is of >10000, >10000, 43.0, 410.6 nM for hCAI, hCAII, hCAIV, hCAIX, respectively.

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CAS No.: 2451479-58-4
Formule: C₁₈H₁₂FNO₃
Masse moléculaire:309.29

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

hCAIX-IN-7 Chemical Structure

CAS No.: 2451479-58-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Chemical Information
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Description

hCAIX-IN-7 (compound 6c) is a potent and selective hCAIX inhibitor with K_Is of >10000, >10000, 43.0, 410.6 nM for hCAI, hCAII, hCAIV, hCAIX, respectively^[1].

IC₅₀ & Target

K_I: >10000 nM (hCAI); >10000 nM (hCAII); 43.0 nM (hCAIV); 410.6 nM (hCAIX)^[1]

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Chemical Information

CAS No. 2451479-58-4
Masse moléculaire 309.29
Formule C₁₈H₁₂FNO₃
SMILES

O=C(NC1=CC2=C(OC(C=C2)=O)C=C1)/C=C/C3=CC=CC(F)=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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hCAIX-IN-7

Voir tous les produits spécifiques à Isoform Carbonic Anhydrase

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

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Help & FAQs

hCAIX-IN-7 Related Classifications

HY-147665 Related Classifications

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