HL1
Based on 1 Customer Validation
HL1 is a Schiff base ligand. HL1 exhibits chelation-enhanced fluorescence effect when forming complexes and can be used as a fluorescent probe for metal ions. HL1 can be used for the research of cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.86%
- CAS No.: 202828-10-2
- Formule: C11H9ClN4O
- Masse moléculaire:248.67
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
HL1 (3.9-500 μM; 24 h) forms Ni2+ and Cu2+ binuclear complexes that show high cytotoxicity against both MDA-MB-231 breast cancer cells and non-cancerous L-6 myoblast cells[1].
HL1 exhibits photoluminescence at a weak and strong excitation wavelength of 415 nm[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 202828-10-2
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Appearance Solid
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Masse moléculaire 248.67
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Formule C11H9ClN4O
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Color White to yellow
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SMILES
ClC1=NN=C(N/N=C/C2=C(O)C=CC=C2)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 43.75 mg/mL (175.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0214 mL | 20.1070 mL | 40.2139 mL | 100.5348 mL |
| 5 mM | 0.8043 mL | 4.0214 mL | 8.0428 mL | 20.1070 mL | |
| 10 mM | 0.4021 mL | 2.0107 mL | 4.0214 mL | 10.0535 mL | |
| 15 mM | 0.2681 mL | 1.3405 mL | 2.6809 mL | 6.7023 mL | |
| 20 mM | 0.2011 mL | 1.0053 mL | 2.0107 mL | 5.0267 mL | |
| 25 mM | 0.1609 mL | 0.8043 mL | 1.6086 mL | 4.0214 mL | |
| 30 mM | 0.1340 mL | 0.6702 mL | 1.3405 mL | 3.3512 mL | |
| 40 mM | 0.1005 mL | 0.5027 mL | 1.0053 mL | 2.5134 mL | |
| 50 mM | 0.0804 mL | 0.4021 mL | 0.8043 mL | 2.0107 mL | |
| 60 mM | 0.0670 mL | 0.3351 mL | 0.6702 mL | 1.6756 mL | |
| 80 mM | 0.0503 mL | 0.2513 mL | 0.5027 mL | 1.2567 mL | |
| 100 mM | 0.0402 mL | 0.2011 mL | 0.4021 mL | 1.0053 mL |