IAA65
IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 µM. IAA65 can be used for epilepsy research.
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- CAS No.: 2987139-96-6
- Formule: C16H13F6NO2
- Masse moléculaire:365.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
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T-type calcium channel |
In Vitro
IAA65 (50 µM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca2+ channel activation[1].
IAA65 (50 µM; differentiated ND7/23 cells) alters the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca2+ channels, which resulted in a significant increase in the inactivation recovery time of the channels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 2987139-96-6
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Masse moléculaire 365.27
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Formule C16H13F6NO2
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SMILES
O=C(NC1=CC(CC(C)C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)