J-104123
J-104123 is an inhibitor of squalene synthase with monocarboxylic acid structure. J-104123 can lower serum cholesterol level in dog models.
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- CAS No.: 162037-54-9
- Formule: C28H29Cl2NO3
- Masse moléculaire:498.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
2.5 nM
Compound: J-104123
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Inhibitory activity against squalene synthase (SQS) obtained from HepG2 cells
Inhibitory activity against squalene synthase (SQS) obtained from HepG2 cells
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10.1016/0960-894X(96)00033-9 |
Chemical Information
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CAS No. 162037-54-9
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Masse moléculaire 498.44
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Formule C28H29Cl2NO3
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SMILES
O=C(C[C@@H](CC(N[C@@H](C)[C@H](/C=C/C1=CC=C2C=CC=CC2=C1)CC3=CC=C(C(Cl)=C3)Cl)=O)C)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
J-104123 Related Classifications
HY-124374 Related Classifications
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