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Cat. No.: HY-15500

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JM6

JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC₅₀ of 19.85 μM for mouse KMO. JM6 can be used for Alzheimer's diseases research.

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CAS No.: 1008119-83-2
Formule: C₂₃H₂₆N₄O₆S₂
Masse moléculaire:518.61

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

JM6 Chemical Structure

CAS No.: 1008119-83-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
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Activité biologique

Description

JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC₅₀ of 19.85 μM for mouse KMO. JM6 can be used for Alzheimer's diseases research^[1].

IC₅₀ & Target

IC50: 19.85 μM (kynurenine 3-monooxygenase)^[1]

Chemical Information

CAS No. 1008119-83-2
Masse moléculaire 518.61
Formule C₂₃H₂₆N₄O₆S₂
SMILES

O=S(C1=CC=C(OC)C(OC)=C1)(NC2=NC(C3=CC=CC([N+]([O-])=O)=C3)=C(CN4CCCCC4)S2)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Maria G Beconi, et al. Metabolism and pharmacokinetics of JM6 in mice: JM6 is not a prodrug for Ro-61-8048. Drug Metab Dispos. 2012 Dec;40(12):2297-306. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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JM6

High-Throughput Bioactive Compound Library

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

JM6 Related Classifications

HY-15500 Related Classifications