LHQ766
LHQ766 is a highly selective, orally active, covalent FGFR2 inhibitor with an IC50 of 7.3 nM. LHQ766 significantly suppresses phosphorylation of FGFR2 and its downstream signaling molecules FRS2-a, Akt and ERK1/2. LHQ766 selectively suppresses the proliferation of FGFR2-driven cancer cells.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C28H27F2N5O3
- Masse moléculaire:519.54
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
FGFR2 7.3 nM (IC50) |
ERK1 |
ERK2 |
Chemical Information
-
Masse moléculaire 519.54
-
Formule C28H27F2N5O3
-
SMILES
CC(C=C1NC(C(F)=C)=O)=C(C=C1)C2=C(C3=C(N=CN=C3N2C)N)C4=CC(F)=C(C=C4)C5(COC5)OCC
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LHQ766 Related Classifications
HY-180794 Related Classifications
Powered by Bioz