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MEDI-2045

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Based on 1 Customer Validation

MEDI-2045 is a humanized antibody expressed in CHO cells that targets IL-4Ra/CD124. MEDI-2045 has a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for MEDI-2045 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

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  • Pureté: 99.99%
  • Masse moléculaire:143.76 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for MEDI-2045
  • Experimental Validation Results for MEDI-2045
  • Experimental Validation Results for MEDI-2045
  • MEDI-2045 Chemical Structure
    MEDI-2045 Chemical Structure
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MEDI-2045 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized IL-4Rα-ECD-C-6His can bind MEDI-2045. The EC50 for this effect is 211.3 ng/mL.

  • 1/16

    Flow Cytometry analysis of Daudi cells labelling IL-4Ra (red) with MEDI-2045 (anti-IL-4Ra) (HY-P990624). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control.

  • MEDI-2045 Chemical Structure
    1/16
  • MEDI-2045
  • Immobilized IL-4Rα-ECD-C-6His can bind MEDI-2045. The EC50 for this effect is 211.3 ng/mL.
  • Flow Cytometry analysis of Daudi cells labelling IL-4Ra (red) with MEDI-2045 (anti-IL-4Ra) (HY-P990624). Cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99991, blue) was used as the isotype control.
  • IgG1-kappa