Methyl salvionolate A
Methyl salvionolate A is a potent inhibitor of HIV-1. Methyl salvionolate A inhibits P24 antigen in HIV-1 infected MT-4 cell with an EC50 of 1.62 μg/ml. Methyl salvionolate A also inhibits HIV-1 reverse transcriptase, protease and integrase with IC50s of 50.58, 10.73 and 7.58 μg/ml, respectively.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1015171-69-3
- Formule: C27H24O10
- Masse moléculaire:508.47
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MOLM-13 | IC50 |
6.7 μM
Compound: 14
|
Antiproliferative activity against human MOLM13 cells by Cell-Titer Glo assay
Antiproliferative activity against human MOLM13 cells by Cell-Titer Glo assay
|
[PMID: 30370766] |
| MOLM-14 | IC50 |
>10 μM
Compound: 14
|
Antiproliferative activity against human MOLM14 cells by Cell-Titer Glo assay
Antiproliferative activity against human MOLM14 cells by Cell-Titer Glo assay
|
[PMID: 30370766] |
| MV4-11 | IC50 |
>10 μM
Compound: 14
|
Antiproliferative activity against human MV4-11 cells by Cell-Titer Glo assay
Antiproliferative activity against human MV4-11 cells by Cell-Titer Glo assay
|
[PMID: 30370766] |
Chemical Information
-
CAS No. 1015171-69-3
-
Masse moléculaire 508.47
-
Formule C27H24O10
-
SMILES
OC(C=C1/C=C/C2=C(C=CC(O)=C2O)/C=C/C(O[C@@H](C(OC)=O)CC3=CC(O)=C(C=C3)O)=O)=C(C=C1)O
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Wang Q, et al. Salviachinensines A-F, Antiproliferative Phenolic Derivatives from the Chinese Medicinal Plant Salvia chinensis. J Nat Prod. 2018 Nov 26;81(11):2531-2538. [Content Brief]
[2]. Zhang ZF, et al. Three new derivatives of anti-HIV-1 polyphenols isolated from Salvia yunnanensis. J Asian Nat Prod Res. 2008 May-Jun;10(5-6):391-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Methyl salvionolate A Related Classifications
HY-N11288 Related Classifications
Powered by Bioz