(-)-7-Methoxyrosmanol
Based on 1 Customer Validation
(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization, can induce cell cycle arrest and apoptosis in neuroblastoma cells.
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- Pureté : 99.53%
- CAS No.: 24703-38-6
- Formule: C21H28O5
- Masse moléculaire:360.44
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Stockage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
35.6 μM
Compound: 7
|
Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| A549 | IC50 |
50.8 μM
Compound: 7
|
Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| HeLa | IC50 |
>60 μM
Compound: 7
|
Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| HeLa | IC50 |
40.8 μM
Compound: 7
|
Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| MCF7 | IC50 |
23.3 μM
Compound: 7
|
Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| MCF7 | IC50 |
41.1 μM
Compound: 7
|
Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| Vero | IC50 |
33.9 μM
Compound: 7
|
Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
| Vero | IC50 |
36.7 μM
Compound: 7
|
Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay
Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay
|
[PMID: 19711987] |
Chemical Information
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CAS No. 24703-38-6
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Appearance Solid
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Masse moléculaire 360.44
-
Formule C21H28O5
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Color Light yellow to light brown
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SMILES
O=C1[C@]23[C@@](C(C)(CCC3)C)([H])[C@@H]([C@@H](C4=CC(C(C)C)=C(O)C(O)=C42)OC)O1.[Rotation (-)]
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Synonyms
(-)-7-O-Methoxyrosmanol
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Structure Classification
-
Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Pureté et documentation
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Fiche technique (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)