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Cat. No.: HY-118202

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(-)-Gallopamil

(Synonyms: (-)-Methoxyverapamil)

(-)-Gallopamil exerts a selective modulation of the fast voltage-dependent inactivation. (-)-Gallopamil inhibits efficiently Cav1.2 constructs formed by β-subunits (promoting fast voltage-dependent inactivation). (-)-Gallopamil also accelerates the voltage-dependent phase of I_Ca decay (as well as the voltage-dependent decay of Ba²⁺ currents). (-)-Gallopamil is promising for research of antiarrhythmics.

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CAS No.: 36622-40-9
Formule: C₂₈H₄₀N₂O₅
Masse moléculaire:484.63

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(-)-Gallopamil Chemical Structure

CAS No.: 36622-40-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 36622-40-9
Masse moléculaire 484.63
Formule C₂₈H₄₀N₂O₅
SMILES

N#C[C@](CCCN(C)CCC1=CC=C(C(OC)=C1)OC)(C2=CC(OC)=C(C(OC)=C2)OC)C(C)C
Synonyms

(-)-Methoxyverapamil
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sokolov S, et al. On the role of Ca(2+)- and voltage-dependent inactivation in Ca(v)1.2 sensitivity for the phenylalkylamine (-)gallopamil. Circ Res. 2001 Oct 12;89(8):700-8. [Content Brief]

[2]. Sokolov S, et al. Inactivation determinant in the I-II loop of the Ca2+ channel alpha1-subunit and beta-subunit interaction affect sensitivity for the phenylalkylamine (-)gallopamil. J Physiol. 1999 Sep 1;519 Pt 2(Pt 2):315-22. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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(-)-Gallopamil

Voir tous les produits spécifiques à Isoform Calcium Channel

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(-)-Gallopamil Related Classifications

HY-118202 Related Classifications