Miricorilant
Miricorilant (CORT 118335) is a dual selective glucocorticoid (GR) modulator/mineralocorticoid (MR) antagonist. Miricorilant can be used for the research of hypothalamic-pituitary-adrenal (HPA) axis related disorders.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1400902-13-7
- Formule: C24H23F3N2O2
- Masse moléculaire:428.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Glucocorticoid/Mineralocorticoid[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (≈250 g)[1]
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Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg
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Administration:Subcutaneously (s.c.); five days.
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Result:30 mg/kg had lower corticosterone responses relative to 10 mg/kg at 15 and 30 min time points.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1400902-13-7
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Masse moléculaire 428.45
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Formule C24H23F3N2O2
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SMILES
O=C1NC(C(CC2=CC=CC(C(F)(F)F)=C2)=C(N1)[C@H]3CC[C@@H](CC3)C4=CC=CC=C4)=O
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Synonyms
CORT 118335
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Miricorilant Related Classifications
HY-117965 Related Classifications
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