MK-3984
MK-3984 is a selective androgen receptor modulator that stimulates anabolic pathways in muscle and bone. MK-3984 can be used in research related to muscle wasting and related conditions.
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- CAS No.: 871325-55-2
- Formule: C17H12F7NO2
- Masse moléculaire:395.27
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
The androgen receptor (AR) is a ligand-dependent nuclear transcription factor that, upon binding androgens, translocates into the nucleus to regulate the transcription of target genes, mediating reproduction, tissue growth, and tumor cell proliferation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 871325-55-2
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Masse moléculaire 395.27
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Formule C17H12F7NO2
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SMILES
FC(F)(F)C1=CC=C(F)C(CNC([C@](O)(C2=CC=CC=C2)C(F)(F)F)=O)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)