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Cat. No.: HY-181881

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MV78-OH

MV78-OH is a NAMPT ligand that can be used as a target protein ligand to synthesize NAMPT-targeting PROTACs, such as PROTAC NAMPT Degrader-28 (HY-181880).

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Formule: C₂₇H₂₉N₅O₂
Masse moléculaire:455.55

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MV78-OH Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

MV78-OH is a NAMPT ligand that can be used as a target protein ligand to synthesize NAMPT-targeting PROTACs, such as PROTAC NAMPT Degrader-28 (HY-181880)^[1].

Chemical Information

Masse moléculaire 455.55
Formule C₂₇H₂₉N₅O₂
SMILES

O=C(NCCCCCCCN1N=NC(C2=CC=CN=C2)=C1)C3=CC=CC=C3C4=CC=CC(O)=C4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Galli U, et al. Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy. J Med Chem. 2026;69(5):5259-5290. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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