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Cat. No.: HY-W673649

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N-Oleyl-sphingomyelin

N-Oleyl-sphingomyelin is a bilayer property lipid modulator with affinity for cholesterol bilayers. N-Oleyl-sphingomyelin reduces the amount of cholesterol required for liquid-ordered phase formation and enhances the cholesterol tolerance of membrane structures. N-Oleyl-sphingomyelin can be used in studies related to membrane lipid phase separation and lipid raft structures.

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CAS No.: 108392-10-5
Formule: C₄₁H₈₁N₂O₆P
Masse moléculaire:729.08

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Please store the product under the recommended conditions in the Certificate of Analysis.

N-Oleyl-sphingomyelin Chemical Structure

CAS No.: 108392-10-5

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Activité biologique

Description

In Vitro

N-Oleyl-sphingomyelin vesicles show higher affinity for cholesterol than POPC vesicles, and can form a liquid-ordered phase at lower cholesterol concentrations; their mixed vesicles with N-palmitoyl-sphingomyelin exhibit only a single phase transition, with asymmetric differences in the miscibility of components between the two phases^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 108392-10-5
Masse moléculaire 729.08
Formule C₄₁H₈₁N₂O₆P
SMILES

[C@H](NC(CCCCCCC/C=C\CCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])[C@@H](/C=C/CCCCCCCCCCCCC)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Halling KK, Ramstedt B, Nyström JH, et al. Cholesterol interactions with fluid-phase phospholipids: effect on the lateral organization of the bilayer. Biophysical journal. 2008 Oct;95(8):3861-71. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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