Nafenodone
Nafenodone is an antidepressant agent. Nafenodone can reduce the rate and amplitude of contractions and lengthen sinus node recovery time. Nafenodone can inhibit the spontaneous mechanical activity in portal vein segmens with an IC50 of 1.4 μM in rat isolated vascular smooth muscle. Nafenodone relaxes the contractions induced by high K+ and noradrenaline.
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- CAS No.: 92615-20-8
- Formule: C20H23NO
- Masse moléculaire:293.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 92615-20-8
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Masse moléculaire 293.40
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Formule C20H23NO
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SMILES
O=C1C2=C(CCC1(CCN(C)C)C3=CC=CC=C3)C=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Pérez-Vizcaino, F., et al., (1991). Effects of (S)-nafenodone, a new antidepressant, in isolated guinea-pig atrial and ventricular muscle fibres. European journal of pharmacology, 199(1), 43-50. [Content Brief]
[2]. Pérez-Vizcaíno, F., et al., (1993). Effects of (S)-nafenodone on 45Ca2+ fluxes and contractions in rat isolated vascular smooth muscle. European journal of pharmacology, 232(1), 105-111. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nafenodone Related Classifications
HY-165387 Related Classifications
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