ND-654
ND-654 is a highly selective acetyl-CoA carboxylase (ACC) inhibitor (IC50: ACC1=3 nM, ACC2=8 nM). ND-654 reduces hepatic lipogenesis, decreases neutrophil recruitment and promotes anti-inflammatory M2 macrophage polarization. ND-654 is promising for research of nonalcoholic steatohepatitis and hepatocellular carcinoma.
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- CAS No.: 1434641-55-0
- Formule: C29H33N3O8S
- Masse moléculaire:583.65
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
Chemical Information
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CAS No. 1434641-55-0
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Masse moléculaire 583.65
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Formule C29H33N3O8S
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SMILES
CC(C)(N(C(N(C[C@H](O[C@H]1CC[C@@H](O)CC1)C2=CC=CC=C2OC)C3=C4C(C)=C(C5=NC=CO5)S3)=O)C4=O)C(O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ND-654 Related Classifications
HY-127108 Related Classifications
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