Nocathiacin Ⅲ
Nocathiacin III (Nocathiacine III) is highly resistant to Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF).
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- CAS No.: 256230-47-4
- Formule: C52H43N13O16S5
- Masse moléculaire:1266.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 256230-47-4
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Masse moléculaire 1266.30
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Formule C52H43N13O16S5
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SMILES
ON1C2=CC=CC3=C2C4=C1C(OC[C@@]5([H])C6=NC(C7=NC(C8=NC(C(NC(C(N)=O)=C)=O)=CS8)=C(O)C=C7C9=NC(C(N[C@@](C(N/C(C%10=NC(C(N[C@@](C%11=NC(C(N5)=O)=CS%11)([H])[C@]([C@@H](C(OC3)=O)O)([H])OC4)=O)=CS%10)=C(C)/OC)=O)([H])[C@H](O)C)=O)=CS9)=CS6)=O
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Synonyms
Nocathiacine III
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Structure Classification
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Initial Source
Nocardia sp.
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)