Nur77 modulator 2
Nur77 modulator 2, a Nur77 modulator (Kd of 0.35 μM), is a potent and orally active inflammation inhibitor. Nur77 modulator 2 modulates the colocalization of Nur77 at mitochondria.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2055829-03-1
- Formule: C26H25NO5
- Masse moléculaire:431.48
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Protocole
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Nuclear Hormone Receptor 4A/NR4A
More
Activité biologique
Description
IC50 & Target
|
Nur77/NR4A1 |
In Vitro
Nur77 modulator 2 (Compound B7) significantly decreases the production of cytokines in vitro, such as NO, IL-6, IL-1β, and TNF-α, at concentrations of 1.25 μM, 2.5 μM, and 5 μM. Nur77 modulator 2 inhibits the lipopolysaccharides (LPS)-induced inflammation via the blockade of NF-κB activation in a Nur77-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2055829-03-1
-
Masse moléculaire 431.48
-
Formule C26H25NO5
-
SMILES
O=C(NO)C1=CC=C(C2=CC(C3=CC(O)=CC(C4(C5)CC6CC5CC(C6)C4)=C3O2)=O)C=C1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nur77 modulator 2 Related Classifications
HY-115923 Related Classifications
Powered by Bioz