OTS447
Based on 1 Customer Validation
OTS447 is a potent FLT3 inhibitor with an IC50 of 21 nM (WO2012016082A1, compound 335).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.83%
- CAS No.: 1356943-67-3
- Formule: C27H32ClN3O2
- Masse moléculaire:466.01
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
Chemical Information
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CAS No. 1356943-67-3
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Appearance Solid
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Masse moléculaire 466.01
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Formule C27H32ClN3O2
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Color Light yellow to yellow
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SMILES
CC(C1=C(NC2CCC(N(CC)CC)CC2)C3=CC(C4=CC=C(O)C(Cl)=C4)=CC=C3N=C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 12.41 mg/mL (26.63 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1459 mL | 10.7294 mL | 21.4588 mL | 53.6469 mL |
| 5 mM | 0.4292 mL | 2.1459 mL | 4.2918 mL | 10.7294 mL | |
| 10 mM | 0.2146 mL | 1.0729 mL | 2.1459 mL | 5.3647 mL | |
| 15 mM | 0.1431 mL | 0.7153 mL | 1.4306 mL | 3.5765 mL | |
| 20 mM | 0.1073 mL | 0.5365 mL | 1.0729 mL | 2.6823 mL | |
| 25 mM | 0.0858 mL | 0.4292 mL | 0.8584 mL | 2.1459 mL |