PD-149164
PD-149164 is a potent agonist of cholecystokinin B (CCK-B) receptor, with IC50 values of 0.083 nM and 75 nM in binding assay to CCK-B and CCK-A.
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- CAS No.: 181941-32-2
- Formule: C33H38FN3O5
- Masse moléculaire:575.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
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CCKAR 75 nM (IC50) |
CCKBR 0.083 nM (IC50) |
Chemical Information
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CAS No. 181941-32-2
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Masse moléculaire 575.67
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Formule C33H38FN3O5
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SMILES
O=C(C[C@H](CC1=CC=C(C=C1)F)NC([C@@](NC(OC2C3CC4CC(CC2C4)C3)=O)(C)CC5=CNC6=C5C=CC=C6)=O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)