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Cat. No.: HY-118172

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PD-307243

PD-307243 is a hERG channel activator. PD-307243 can be used for research of arrhythmias.

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CAS No.: 313533-41-4
Formule: C₂₀H₁₅Cl₂N₃O₂
Masse moléculaire:400.26

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PD-307243 Chemical Structure

CAS No.: 313533-41-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
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Classifications
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Activité biologique

Description

PD-307243 is a hERG channel activator. PD-307243 can be used for research of arrhythmias^[1].

In Vitro

PD-307243 (3 and 10 μM) induces instantaneous hERG current in CHO cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 313533-41-4
Masse moléculaire 400.26
Formule C₂₀H₁₅Cl₂N₃O₂
SMILES

O=C(O)C1=CC=CN=C1NC2=CC3=C(C=C2)CN(C3)C4=CC=C(C(Cl)=C4)Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Gordon E, et al. 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels. Mol Pharmacol. 2008 Mar;73(3):639-51. [Content Brief]

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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PD-307243

High-Throughput Bioactive Compound Library

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

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PD-307243 Related Classifications

HY-118172 Related Classifications