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Cat. No.: HY-135628

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PD-85639

PD-85639 is a voltage-gated sodium (Na+) channel blocker that has neuroprotective effects.

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CAS No.: 149838-21-1
Formule: C₂₄H₃₂N₂O
Masse moléculaire:364.52

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PD-85639 Chemical Structure

CAS No.: 149838-21-1

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Quantité

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

PD-85639 is a voltage-gated sodium (Na+) channel blocker that has neuroprotective effects^[1]^[2].

Voir tous les produits spécifiques à Isoform Sodium Channel :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO	IC₅₀	2.7 μM Compound: 1	Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cells Inhibitory activity against type IIA sodium channel in CNaIIA-1 cell line expressed in CHO cells	[PMID: 8691482]

Chemical Information

CAS No. 149838-21-1
Masse moléculaire 364.52
Formule C₂₄H₃₂N₂O
SMILES

O=C(NCCCN1C(C)CCCC1C)C(C2=CC=CC=C2)C3=CC=CC=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. A V Shindikar, et al. Design, synthesis and in vivo anticonvulsant screening in mice of novel phenylacetamides. Eur J Med Chem. 2006 Jun;41(6):786-92. [Content Brief]

[2]. Ioannis Roufos, et al. A Structure-Activity Relationship Study of Novel Phenylacetamides Which Are Sodium Channel Blockers. J. Med. Chem. 1996, 39, 1514-1520.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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