PHOME
Based on 1 Customer Validation
PHOME is a fluorogenic substrate for sEH. sEH can hydrolyze the epoxy ring in the PHOME substrate. PHOME can be used for fluorescent epoxide hydrolase assay.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.9%
- CAS No.: 1028430-42-3
- Formule: C23H19NO4
- Masse moléculaire:373.40
-
Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
-
Solvant et solubilité
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
PHOME enters the sEH active site and is hydrolyzed by sEH to generate the fluorescent product 6-methoxy-2-naphthaldhyde. The fluorescence intensity of 6-methoxy-2-naphthaldhyde can be detected by a fluorescence detector to evaluate the activity of sEH or the efficacy of sEH inhibitors[2].
PHOME can be used to develop the liquid chromatography-biochemical detection (LC-BCD) system for efficient screening and quantitative analysis of sEH inhibitors[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1028430-42-3
-
Appearance Solid
-
Masse moléculaire 373.40
-
Formule C23H19NO4
-
Color White to off-white
-
SMILES
O=C(OC(C#N)C1=CC=C2C=C(OC)C=CC2=C1)CC3OC3C4=CC=CC=C4
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 25 mg/mL (66.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMSO : ≥ 10 mg/mL (26.78 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
-
Fiche technique (274 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / DMSO | 1 mM | 2.6781 mL | 13.3905 mL | 26.7809 mL | 66.9523 mL |
| 5 mM | 0.5356 mL | 2.6781 mL | 5.3562 mL | 13.3905 mL | |
| 10 mM | 0.2678 mL | 1.3390 mL | 2.6781 mL | 6.6952 mL | |
| 15 mM | 0.1785 mL | 0.8927 mL | 1.7854 mL | 4.4635 mL | |
| 20 mM | 0.1339 mL | 0.6695 mL | 1.3390 mL | 3.3476 mL | |
| 25 mM | 0.1071 mL | 0.5356 mL | 1.0712 mL | 2.6781 mL | |
| DMSO | 30 mM | 0.0893 mL | 0.4463 mL | 0.8927 mL | 2.2317 mL |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6695 mL | 1.6738 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5356 mL | 1.3390 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4463 mL | 1.1159 mL |
PHOME Related Classifications
HY-113862 Related Classifications
Powered by Bioz