TSSK
The TSSK group encodes testis-specific serine/threonine kinases, a CAMK-family branch expressed exclusively in male germ cells after meiosis. Members TSSK1 through TSSK6 are transcribed in spermatids, where they remodel chromatin, shape the sperm head, and assemble the flagellum and mitochondrial sheath required for motility. Gene knockout studies in mice demonstrate that several members are indispensable for male fertility while remaining dispensable elsewhere, a specificity making them attractive non-hormonal contraceptive targets. TSSK6-null males, for example, produce sperm with defective chromatin condensation. Structural studies support development of selective inhibitors, and immunological detection of TSSKs in sperm has been explored for fertility diagnostics.
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TSSK Protéines Recombinantes (5)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formule: Human
- Masse moléculaire: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
