TSSK4
TSSK4, encoded by STK31, is the family member whose activity is directly switched on by another TSSK: TSSK6/SSTK phosphorylates its activation loop, establishing the only known kinase phosphorylation cascade inside the TSSK group. Although first described in germ cells, TSSK4 transcripts are detectable in a range of somatic tissues and are elevated in several cancers, including leukemia and glioma, where it may support proliferation. Like its siblings, TSSK4 possesses a CAMK-type catalytic domain but little is known about its physiological substrates. Recombinant TSSK4 produced with TSSK6 provides active enzyme for inhibitor screening and substrate discovery.
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TSSK4 Recombinant Proteins (2)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
