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Cat. No.: HY-N13355

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Przewaquinone B

Name: Przewaquinone B
Brand: MedChemExpress
SKU: HY-N13355
Price: 600.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Przewaquinone B is an abietane-type diterpene quinone (tanshinone) and a diterpenoid compound. Przewaquinone B can be isolated from the rhizomes of Salvia miltiorrhiza Bunge, the roots of Salvia przewarskii, and the roots of Salvia constanea. Przewaquinone B exhibits antitumor activity against cervical cancer and promyelocytic leukemia. Przewaquinone B can be used in research related to cervical cancer and promyelocytic leukemia.

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CAS No.: 76829-01-1
Formule: C₁₈H₁₂O₄
Masse moléculaire:292.29

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Przewaquinone B Chemical Structure

CAS No.: 76829-01-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
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Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
KB	IC₅₀	3.22 μM Compound: 6	Antiproliferative activity against human KB cells after 72 hrs by sulforhodamine B assay Antiproliferative activity against human KB cells after 72 hrs by sulforhodamine B assay	[PMID: 29294282]
HeLa	IC50	19.0 μM	Cytotoxicity against human cervical cancer HeLa cells. Cytotoxicity against human cervical cancer HeLa cells.	27032190
HL-60	IC50	3.0 μM	Cytotoxicity against human promyelocytic leukemia HL-60 cells. Cytotoxicity against human promyelocytic leukemia HL-60 cells.	27032190

In Vitro

Przewaquinone B exhibits weak cytotoxicity against HeLa cells (IC₅₀ = 19.0 μM) and significant cytotoxicity against HL-60 cells (IC₅₀ = 3.0 μM)^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 76829-01-1
Masse moléculaire 292.29
Formule C₁₈H₁₂O₄
SMILES

O=C1C(C2=C(C3=C1C(C=CC=C4C)=C4C=C3)OC=C2CO)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Wang X, et al. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med Res Rev. 2007 Jan;27(1):133-48. [Content Brief]

[2]. Tsukada H, et al. Two New Diterpenoids from Salvia przewarskii. Natural product communications. 2016 Feb;11(2):159-61. [Content Brief]

[3]. YANG M H, et al. Diterpenoids from Salvia species[J]. Pharmacy and Pharmacology Communications, 1996, 2(1): 69-71.

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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