QS-S2
QS-S2 is the impurity of QS-21 (HY-101092A). QS-21 is an innate immune system-targeted adjuvant.
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- CAS No.: 250643-52-8
- Formule: C87H140O42
- Masse moléculaire:1858.02
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
QS-21 is a mixture of QS-21-Xyl (250643-56-2) and QS-21-Api (141256-04-4), with a ratio of 35:65. QS-21 is promising for research of oncology vaccines (e.g., melanoma) and infectious disease vaccines (e.g., HIV, malaria)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 250643-52-8
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Masse moléculaire 1858.02
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Formule C87H140O42
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SMILES
O[C@H]([C@@H]([C@H]([C@@H](O1)C)O[C@H]2[C@@H]([C@H]([C@@H](CO2)O)O)O)O)[C@@H]1O[C@H]([C@H]([C@H]([C@H](O3)C)OC(C[C@@H](O)C[C@@H]([C@@H](C)CC)OC(C[C@@H](O)C[C@@H]([C@@H](C)CC)O[C@@H]4O[C@H]([C@@H]([C@H]4O)O)CO)=O)=O)O)[C@@H]3OC([C@]56[C@](CC(C)(CC6)C)([H])C7=CC[C@@]([C@@]8([C@@]([C@@](C)([C@H](CC8)O[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)C(O)=O)O)O[C@H]%10[C@@H]([C@H]([C@@H](CO%10)O)O)O)O[C@@H]%11O[C@@H]([C@@H]([C@@H]([C@H]%11O)O)O)CO)C=O)([H])CC%12)C)([H])[C@]%12(C)[C@@]7(C[C@H]5O)C)=O
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Bankefors J, et al. Structural classification of acyl-substituted Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry in combination with multivariate analysis. Rapid Commun Mass Spectrom. 2008 Dec;22(23):3851-60. [Content Brief]
[2]. Deng K, et al. Synthesis of QS-21-xylose: establishment of the immunopotentiating activity of synthetic QS-21 adjuvant with a melanoma vaccine. Angew Chem Int Ed Engl. 2008;47(34):6395-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
QS-S2 Related Classifications
HY-N16463 Related Classifications
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