country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P11625

Copy Link Print Information

R9-13

R9-13 is a fatty acid-conjugated relaxin and an agonist of LGR7 (RXFP1). R9-13 induces sustained pubic symphysis elongation in estrogen-pretreated mice. R9-13 exhibits long-acting pharmacokinetic profiles in rodents, with in vivo activity lasting up to one week after administration. R9-13 can be used in studies related to acute heart failure.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₂₉₄H₄₇₈N₇₈O₈₃S₉
Masse moléculaire:6722.00

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

R9-13 Chemical Structure

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

In Vivo

R9-13 (0.9-30 nmol/kg (30 μg/kg); single dose; administered via injection) exhibits a dose-dependent and sustained pubic ligament elongation (PLE) effect in estrogen-pretreated female CD1 mice, with an ED₅₀ of 5 nmol/kg^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

CD1 (female; estrogen-primed)^[1]
Dosage:

0.9, 3.0, 9, 30 nmol/kg; 1, 10, 30 nmol/kg
Administration:

single dose; measured at 168 h after treatment
Result:

Observed dose-responsive pubic ligament elongation at 24 hours post-dosing; sustained elongation effect at 168 hours post-dosing.

Chemical Information

Masse moléculaire 6722.00
Formule C₂₉₄H₄₇₈N₇₈O₈₃S₉
Sequence

Chain1:{pGln}-Cys(carbamic acid-PEG2-carbamic acid-PEG2-Lys-C18diacid)-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Ile-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys; Chain2:Ala-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser (Disulfidebridge:Chain 1 Cys10-Chain 1 Cys15,Chain 1 Cys11-Chain 2 Cys11,Chain 1 Cys24-Chain 2 Cys23
Sequence Shortening

Chain1:{pGln}-Cys(carbamic acid-PEG2-carbamic acid-PEG2-Lys-C18diacid)-YSALANKCCHVGCIKRSLARFC; Chain2:ASWMEEVIKLCGRELVRAQIAICGMSTWS (Disulfidebridge:Chain 1 Cys10-Chain 1 Cys15,Chain 1 Cys11-Chain 2 Cys11,Chain 1 Cys24-Chain 2 Cys23
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Muppidi A, et al. Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs. Bioconjug Chem. 2019;30(1):83-89. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis