Retinyl glucoside
Retinyl glucoside (Retinyl β-D-glucoside) is a lipid β-D-glucoside of retinol, and also serves as a substrate for broad-spectrum β-glucosidase (β-glucosidase). Retinyl glucoside can be hydrolyzed by guinea pig hepatocyte cytosolic and membrane-associated β-glucosidases as well as almond β-glucosidase to release retinol and glucose, but it is not hydrolyzed by human placental glucocerebrosidase. Retinyl glucoside can be used in the research of Gaucher's disease.
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- CAS No.: 136778-12-6
- Formule: C26H40O6
- Masse moléculaire:448.59
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Retinyl glucoside (60 min) can be hydrolyzed by almond β-glucosidase in 0.1 M sodium acetate (pH 5.5), releasing nearly equimolar amounts of retinol and glucose, with a glucose/retinol molar ratio of 0.99[1].
Retinyl glucoside (60 min) can be hydrolyzed by guinea pig hepatocellular cytosolic β-glucosidase and membrane-associated TX-100 β-glucosidase in 0.2 M Sodium Citrate (HY-B2201) (pH 6.0)[1].
Retinyl glucoside (1 h) is not hydrolyzed by human placental glucocerebrosidase in 0.1 M sodium acetate (pH 5.5) containing TdC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136778-12-6
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Appearance Solid
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Masse moléculaire 448.59
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Formule C26H40O6
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Color Yellow to brown
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SMILES
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)=C(C)CCC1
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Synonyms
Retinyl β-D-glucoside
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Retinyl glucoside Related Classifications
HY-A0058 Related Classifications
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Keywords
- Retinyl glucoside
- 136778-12-6
- Retinyl β-D-glucoside
- Glycosidase
- retinol
- guinea pig liver membrane-associated (TX-100) β-glucosidase
- gaucher disease
- p-nitrophenyl β-D-glucopyranoside
- human placental glucocerebrosidase
- glucocerebroside
- guinea pig liver cytosolic β-glucosidase
- pNPGlc
- almond β-D-glucosidase
- glucocerebrosidase
- Inhibitor
- inhibitor
- inhibit