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Cat. No.: HY-146694

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RIPK2-IN-1

RIPK2-IN-1 (compound 18f) is a potent RIPK2 inhibitor with an IC₅₀ of 51 nM. RIPK2-IN-1 inhibits ALK2 with an IC₅₀ of 5 nM. RIPK2-IN-1 has an IC₅₀ of 390 nM on RIPK2/NOD2 in cell assay.

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CAS No.: 2245820-70-4
Formule: C₂₃H₂₇N₅O₃S
Masse moléculaire:453.56

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

RIPK2-IN-1 Chemical Structure

CAS No.: 2245820-70-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform RIP kinase :

Chemical Information

CAS No. 2245820-70-4
Masse moléculaire 453.56
Formule C₂₃H₂₇N₅O₃S
SMILES

COC1=CC(C2=C(N=CC(C3=CC=C(C=C3)N4CCNCC4)=C2)N)=CC(NS(C)(=O)=O)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chalada Suebsuwong, et al. Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. Eur J Med Chem. 2020 Aug 15;200:112417. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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RIPK2-IN-1

Voir tous les produits spécifiques à Isoform RIP kinase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RIPK2-IN-1 Related Classifications

HY-146694 Related Classifications