country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-182453

Copy Link Print Information

RM1490

RM1490 (Compound 251) acts as an inhibitor of μ-opioid receptor (MOR) (IC₅₀ ≤ 300 nM), an activator of δ-opioid receptor (DOR) (EC₅₀ > 3000 nM), and an inhibitor of κ-opioid receptor (KOR) (IC₅₀ ≤ 300 nM). RM1490 is applicable to the research of neuropsychiatric disorders.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2849392-47-6
Formule: C₂₅H₃₄N₂O₂
Masse moléculaire:394.55

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

RM1490 Chemical Structure

CAS No.: 2849392-47-6

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

μ Opioid Receptor/MOR

≤ 300 nM (IC₅₀)

δ Opioid Receptor/DOR

> 3000 nM (EC₅₀)

κ Opioid Receptor/KOR

≤ 300 nM (IC₅₀)

Voir tous les produits spécifiques à Isoform Opioid Receptor :

In Vitro

RM1490 (Compound 251) (Serially diluted concentrations; 15 minutes at 37°C, 5% CO₂ plus 15 minutes at room temperature) potently antagonizes the mu opioid receptor in CHO Tag-lite human mOR stable cells with an IC₅₀ ≤ 300 nM^[1].
RM1490 (Compound 251) acts as a weak agonist of the delta opioid receptor with an EC₅₀ > 3000 nM^[1].
RM1490 (Compound 251) potently antagonizes kappa opioid receptor β-arrestin signaling with an IC₅₀ ≤ 300 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2849392-47-6
Masse moléculaire 394.55
Formule C₂₅H₃₄N₂O₂
SMILES

CC(C=C(C=C1C)O)=C1C[C@H](N(C)C)CNC(C[C@H](C2=CC=CC=C2)C3CC3)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Julio Cesar Medina, et al. Opioid receptor modulators. WO2022216750A1. WIPO (PCT). 2022-04-05.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Amount: USD 0.00

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

RM1490

Voir tous les produits spécifiques à Isoform Opioid Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RM1490 Related Classifications

HY-182453 Related Classifications