(S)-Baclofen
(S)-Baclofen is a GABAB receptor agonist that crosses the blood-brain barrier and is orally active, with IC50 values of 1.77 μM for GABAB and 1564 μM for GABAA. (S)-Baclofen can be used in research on muscle disorders such as spasticity.
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- Pureté: 99.94%
- CAS No.: 66514-99-6
- Formule: C10H12ClNO2
- Masse moléculaire:213.66
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 66514-99-6
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Appearance Solid
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Masse moléculaire 213.66
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Formule C10H12ClNO2
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Color White to off-white
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SMILES
O=C(C[C@@H](C1=CC=C(C=C1)Cl)CN)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
Références
[1]. Froestl W, et al. Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists. J Med Chem. 1995;38(17):3297-3312. [Content Brief]
[2]. He Q, et al. Simultaneous Quantitation of S(+)- and R(-)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC-APCI-MS/MS: An Application for Clinical Studies. Molecules. 2020 Jan 8;25(2):250. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-Baclofen Related Classifications
HY-B0007B Related Classifications
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