SD 8381
SD 8381 is a potent and selective COX-2 inhibitor. SD 8381 shows IC50 values of 0.0098 μM for hCOX-2 and 0.69 μM for hCOX-1.
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- CAS No.: 215123-80-1
- Formule: C11H5Cl2F3O3
- Masse moléculaire:313.06
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
hCOX-1 0.69 μM (IC50) |
hCOX-2 0.0098 μM (IC50) |
Chemical Information
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CAS No. 215123-80-1
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Masse moléculaire 313.06
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Formule C11H5Cl2F3O3
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SMILES
ClC1=C2C(C=C([C@H](O2)C(F)(F)F)C(O)=O)=CC(Cl)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SD 8381 Related Classifications
HY-108019 Related Classifications
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