Septide
Based on 1 Customer Validation
Septide ((Pyr6,Pro9)-Substance P) is a potent NK1 receptor agonist with a Kd value of 0.55 nM.
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- Pureté: 98.97%
- CAS No.: 79775-19-2
- Formule: C39H53N7O7S
- Masse moléculaire:763.95
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Kd: 0.55 ± 0.03 nM (NK1 receptor)[1]
Septide increases inositol phosphate levels (4-6-fold) in NK1 receptor expressed CHO cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 79775-19-2
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Appearance Solid
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Masse moléculaire 763.95
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Formule C39H53N7O7S
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Color White to off-white
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Synonyms
(Pyr6,Pro9)-Substance P
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Sequence Shortening
Glp-FFPLM-NH2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 100 mg/mL (130.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (281 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Hastrup H, Schwartz TW. Septide and neurokinin A are high-affinity ligands on the NK-1 receptor: evidence from homologous versus heterologous binding analysis. FEBS Lett. 1996 Dec 16;399(3):264-6. [Content Brief]
[2]. Pradier L, Mayaux JF, et al. Septide: an agonist for the NK1 receptor acting at a site distinct from substance P. Mol Pharmacol. 1994 Feb;45(2):287-93. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3090 mL | 6.5449 mL | 13.0899 mL | 32.7247 mL |
| 5 mM | 0.2618 mL | 1.3090 mL | 2.6180 mL | 6.5449 mL | |
| 10 mM | 0.1309 mL | 0.6545 mL | 1.3090 mL | 3.2725 mL | |
| 15 mM | 0.0873 mL | 0.4363 mL | 0.8727 mL | 2.1816 mL | |
| 20 mM | 0.0654 mL | 0.3272 mL | 0.6545 mL | 1.6362 mL | |
| 25 mM | 0.0524 mL | 0.2618 mL | 0.5236 mL | 1.3090 mL | |
| 30 mM | 0.0436 mL | 0.2182 mL | 0.4363 mL | 1.0908 mL | |
| 40 mM | 0.0327 mL | 0.1636 mL | 0.3272 mL | 0.8181 mL | |
| 50 mM | 0.0262 mL | 0.1309 mL | 0.2618 mL | 0.6545 mL | |
| 60 mM | 0.0218 mL | 0.1091 mL | 0.2182 mL | 0.5454 mL | |
| 80 mM | 0.0164 mL | 0.0818 mL | 0.1636 mL | 0.4091 mL | |
| 100 mM | 0.0131 mL | 0.0654 mL | 0.1309 mL | 0.3272 mL |
Septide Related Classifications
HY-P2000 Related Classifications
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