Setomagpran
Setomagpran is an antagonist of Mas-related G protein-coupled receptor X2 (MRGPRX2). Setomagpran inhibits MRGPRX2-mediated Gαq protein recruitment signaling, exhibiting an inhibitory IC50 of 236 nM in HEK293T cells transiently expressing MRGPRX2. Setomagpran can be used in research on MRGPR-mediated diseases, such as inflammatory disorders.
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- CAS No.: 2991434-57-0
- Formule: C22H19Cl2F6N5O
- Masse moléculaire:554.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2991434-57-0
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Masse moléculaire 554.32
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Formule C22H19Cl2F6N5O
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SMILES
FC(F)(F)C1=NC(C=CC(Cl)=C2)=C2C(N[C@@H]3C[C@@H](CCC3)NC(C4=CN(N=C4Cl)CC(F)(F)F)=O)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Setomagpran Related Classifications
HY-172438 Related Classifications
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