SID 7969543 (Standard)
SID 7969543 (Standard) is the analytical standard of SID 7969543 (HY-107404). This product is intended for research and analytical applications. SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily.
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- CAS No.: 868224-64-0
- Formule: C24H24N2O7
- Masse moléculaire:452.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 868224-64-0
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Masse moléculaire 452.46
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Formule C24H24N2O7
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SMILES
CCOC(C(C)OC1=C2C(C(N(CC(NC3=CC=C(OCCO4)C4=C3)=O)C=C2)=O)=CC=C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Madoux F, et al. Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening. Mol Pharmacol. 2008;73(6):1776-1784. [Content Brief]
[2]. Roth J, et al. Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds. Bioorg Med Chem Lett. 2008;18(8):2628-2632. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SID 7969543 (Standard) Related Classifications
HY-107404R Related Classifications
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