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SID 7969543 

Cat. No.: HY-107404
Handling Instructions

SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily.

For research use only. We do not sell to patients.

SID 7969543 Chemical Structure

SID 7969543 Chemical Structure

CAS No. : 868224-64-0

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Description

SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily[1][2].

In Vitro

SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively[1].
SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

452.46

Formula

C₂₄H₂₄N₂O₇

CAS No.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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SID 7969543
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