STE-MEK1(13)
STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH ) is a cell permeable ERK1/2 inhibitor (IC50: 13-30 μM). STE-MEK1(13) inhibits ERK1/2 phosphorylation.
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- CAS No.: 566872-15-9
- Formule: C86H153N19O17S
- Masse moléculaire:1757.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
13-30?μM (ERK1/2)[1]
Chemical Information
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CAS No. 566872-15-9
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Masse moléculaire 1757.32
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Formule C86H153N19O17S
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Synonyms
Ste-MPKKKPTPIQLNP-NH₂; ERK Activation Inhibitor Peptide
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Sequence
{Ste}-Met-Pro-Lys-Lys-Lys-Pro-Thr-Pro-Ile-Gln-Leu-Asn-Pro-NH2
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Sequence Shortening
{Ste}-MPKKKPTPIQLNP-NH2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Li G, et al. A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis. Cell Death Differ. 2006 Dec;13(12):2109-17. [Content Brief]
[2]. Whiteman M, et al. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. Osteoarthritis Cartilage. 2006 May;14(5):460-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
STE-MEK1(13) Related Classifications
HY-P5977 Related Classifications
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