Tetraasterane
Tetraasterane is a hydrophobic tag that promotes the degradation of ALK protein. Tetraasterane can be used for synthesis of ALK degrader 3 (HY-182087).
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- CAS No.: 259-77-8
- Formule: C12H16
- Masse moléculaire:160.26
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Tetraasterane (7 days) conjugated with ALK degrader 3 potently inhibits the proliferation of H3122 cells, with an IC50 of 97.77 nM[1].
Tetraasterane (0.05-2 μM; 24 h) conjugated with ALK degrader 3 induces concentration-dependent degradation of ALK protein in H3122 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 259-77-8
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Masse moléculaire 160.26
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Formule C12H16
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SMILES
C12C(CC3C4C2)C5C1CC4C3C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)