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United States

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Cat. No.: HY-189076

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TKL-IN-3

TKL-IN-3 is a potent herbicide targeting SvTKL, with an IC₅₀ of 0.229 mg/L. TKL-IN-3 binds tightly to SvTKL through interactions with specific residues, thereby inducing inhibition of enzyme function. TKL-IN-3 exhibits herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus. TKL-IN-3 can be used in research on the development of green herbicides.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₂₇H₂₆FN₃O₃
Masse moléculaire:459.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TKL-IN-3 Chemical Structure

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Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target

^[1]

SvTKL

229 μg/mL (IC₅₀)

In Vitro

TKL-IN-3 (compound 9o) (0.125-2.0 mg/L; 10 min) potently inhibits SvTKL, with an IC₅₀ of 0.229 mg/L and an inhibition rate of 92.0% at a concentration of 2.00 mg/L^[1].
TKL-IN-3 (20-200 mg/L; 7 days) exhibits potent herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus seedlings. After 7 days of exposure, the root inhibition rate exceeds 86% at a concentration of 200 mg/L, and ranges from 72% to 80% at a concentration of 20.0 mg/L^[1].
TKL-IN-3 (application dose: 37.5-375 g ai/ha; 7 days after treatment) exhibits a post-emergence inhibition rate of over 90% against Digitaria sanguinalis and Amaranthus retroflexus at a dose of 375 g ai/ha, and an inhibition rate of 70.0% at a dose of 37.5 g ai/ha 7 days after application^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 459.51
Formule C₂₇H₂₆FN₃O₃
SMILES

FC1=CC=C(CN2C(C=CC=C3)=C3C(CC(N(CC)CC4=CN=C(C(OC)=O)C=C4)=O)=C2)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Li C, et al. Design, Synthesis, and Herbicidal Activity of Indole-Containing Fusarium Acid Derivatives Targeting Transketolase. Journal of agricultural and food chemistry. 2026 Aug 05;74(30):23303-23313.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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