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Cat. No.: HY-183875

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TMPBM ligand-1

TMPBM ligand-1 (compound d9A1 warhead) is an SLC9A1 ligand. TMPBM ligand-1 can be used for the synthesis of d9A1-2 (HY-183892). TMPBM ligand-1 is applicable to research on cancers such as chronic myeloid leukemia.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2640254-08-4
Formule: C₂₃H₂₄FN₃O₂
Masse moléculaire:393.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TMPBM ligand-1 Chemical Structure

CAS No.: 2640254-08-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target

^[1]

SLC9A1

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2640254-08-4
Masse moléculaire 393.45
Formule C₂₃H₂₄FN₃O₂
SMILES

O=C(O)C1=CC=C(C2=CC=C(F)C(C)=C2)C(N3CCC(C4=C(C)N=CN4)CC3)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Ariel Bensimon, et al. Compounds for targeted degradation of carrier proteins and uses thereof. EP3808741A1. EPO. 2021-04-21.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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