Tyk2-IN-22
Tyk2-IN-22 (Compound A8) is a selective inhibitor for tyrosine kinase 2 (Tyk2), that it inhibits Tyk2, JAK1, and JAK3 with IC50s of 9.7, 148.6, and 883.3 nM, respectively. Tyk2-IN-22 inhibits the downstream STAT5 phosphorylation.
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- CAS No.: 933667-23-3
- Formule: C16H16ClN5O2
- Masse moléculaire:345.78
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
IC50 & Target
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Tyk2 9.7 nM (IC50) |
JAK1 148.6 nM (IC50) |
JAK3 883.3 nM (IC50) |
Chemical Information
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CAS No. 933667-23-3
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Masse moléculaire 345.78
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Formule C16H16ClN5O2
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SMILES
O=C1N2C(NC(C3=CC=C(Cl)C=C3)=N2)=NC(CN4CCOCC4)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tyk2-IN-22 Related Classifications
HY-168339 Related Classifications
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