VHC-7
VHC-7 is a potent and selective adenylyl cyclase type 8 (AC8) agonist, with an EC50 value of 105.2 nM. VHC-7 increases cyclic adenosine monophosphate (cAMP) levels. VHC-7 can be used for the study of central nervous system disorders and heart diseases.
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- CAS No.: 14750-21-1
- Formule: C18H15Cl2NO3
- Masse moléculaire:364.22
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
0.1052 μM
Compound: VHC-7
|
Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
Agonist activity at recombinant human AC8 expressed in human HEK293 cells assessed as fold increase in cAMP level by LANCE Ultra cAMP Detection kit method
|
[PMID: 31776060] |
Chemical Information
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CAS No. 14750-21-1
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Masse moléculaire 364.22
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Formule C18H15Cl2NO3
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SMILES
O=C(C1(CC2=CC=C(Cl)C=C2Cl)C(NC3=C1C=CC=C3)=O)OCC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)