Vin-C01
Vin-C01 is a potent pancreatic β-cells protective agent with an EC50 of 0.22 μM. Vin-C01 effectively promotes β-cell survival and protects β-cells from STZ (HY-13753)-induced apoptosis. Vin-C01 can be used for type 2 diabetes mellitus research.
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- CAS No.: 23173-26-4
- Formule: C20H24N2O
- Masse moléculaire:308.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
EC50: 0.22 µM (pancreatic β-cells)[1]
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| INS1(832/13) | EC50 |
0.22 μM
Compound: Vin-C01
|
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
Cytoprotective activity in rat INS-1 832/13 cells assessed as inhibition of STZ-induced apoptosis incubated for 24 hrs by MTT assay
|
[PMID: 31918073] |
Chemical Information
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CAS No. 23173-26-4
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Masse moléculaire 308.42
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Formule C20H24N2O
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SMILES
[H][C@]12C3=C4CCN1CCC[C@]2(C=C(N3C5=CC=CC=C54)CO)CC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)