Copy Link Print Information

Vortosiran

(Synonyms: RBD4059)

Vortosiran (RBD4059) is a siRNA that inhibits the synthesis of coagulation factor XI (FXI). Vortosiran shows potent inhibitory activity against mouse FXI transcripts with an IC50 of 69 pM; it exerts similar effects on common FXI transcripts from humans and monkeys, with an IC50 of 59 pM. Vortosiran exhibits antithrombotic activity without impairing hemostatic function. Vortosiran can be used in research related to intravascular thrombosis.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • CAS No.: 3061406-99-0
  • Formule: C463H620F7N154O291P39S6
  • Masse moléculaire:14532.10
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Vortosiran Chemical Structure
    Vortosiran Chemical Structure
CAS No.: 3061406-99-0
Size
Prix
Stock
Quantité
Amount: USD 0.00
Please select quantity
or
or

* Veuillez sélectionner la quantité avant d'ajouter des articles.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
  • Activité biologique
  • Chemical Information
  • Pureté et documentation
  • Références
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Keywords

MOQ
Minimum order quantity
100 mg

Obtenir un devis En stock

Other size
Obtenir un devis
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Enregistrer
Sign in to MedChemExpress
Enregistrer un nouveau compte

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Vortosiran Chemical Structure
    Vortosiran Chemical Structure RNA, (Cm-sp-(2'-deoxy-2'-fluoro)A-sp-Gm-Am-Am-(2'-deoxy-2'-fluoro)U-Cm-Cm-Am-Gm-Um-Cm-Cm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)G-Um-Am-Cm-sp-Um-sp-Um), complex with RNA (Gm-sp-Um-sp-Am-Cm-Gm-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-Cm-Um-Gm-Gm-Am-Um-Um-Cm-Um-Gm) 3'-[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl][3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]propyl][3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-2-hydroxy-3-oxopropyl hydrogen phosphate] (1:1)
    1/16
  • RNA, (Cm-sp-(2'-deoxy-2'-fluoro)A-sp-Gm-Am-Am-(2'-deoxy-2'-fluoro)U-Cm-Cm-Am-Gm-Um-Cm-Cm-(2'-deoxy-2'-fluoro)A-Cm-(2'-deoxy-2'-fluoro)G-Um-Am-Cm-sp-Um-sp-Um), complex with RNA (Gm-sp-Um-sp-Am-Cm-Gm-Um-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)G-(2'-deoxy-2'-fluoro)A-Cm-Um-Gm-Gm-Am-Um-Um-Cm-Um-Gm) 3'-[3-[[3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl][3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]propyl][3-[[5-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-1-oxopentyl]amino]propyl]amino]-2-hydroxy-3-oxopropyl hydrogen phosphate] (1:1)