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Cat. No.: HY-W748591R

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Cannflavin A (Standard)

Cannflavin A (Standard) is the analytical standard of Cannflavin A. This product is intended for research and analytical applications. Cannflavin A can be isolated from Cannabis sativa L.. Cannflavin A has anti-cancer, neuroprotective and anti-inflammatory activity. Cannflavin A inhibits Aβ_1-42 aggregation. Cannflavin A also inhibits kynurenine-3-monooxygenase (KMO) (IC₅₀ = 29.4 μM). Cannflavin A activates apoptosis via caspase-3 cleavage. Cannflavin A exerts anti-inflammatory effects by inhibiting pro-inflammatory enzymes, including prostaglandin E2 and cytochrome c oxidases I and II in PC12 cell line.

For research use only. We do not sell to patients.

CAS No.: 76735-57-4
Formula: C₂₆H₂₈O₆
Molecular Weight:436.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cannflavin A (Standard) Chemical Structure

CAS No.: 76735-57-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 76735-57-4
Molecular Weight 436.50
Formula C₂₆H₂₈O₆
SMILES

OC1=C2C(OC(C3=CC(OC)=C(C=C3)O)=CC2=O)=CC(O)=C1C/C=C(C)/CC/C=C(C)\C
Structure Classification
- Flavonoids
- Flavones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Rea KA, et al. Biosynthesis of cannflavins A and B from Cannabis sativa L. Phytochemistry. 2019 Aug;164:162-171. [Content Brief]

[2]. Eggers C, et al. Novel cannabis flavonoid, cannflavin A displays both a hormetic and neuroprotective profile against amyloid β-mediated neurotoxicity in PC12 cells: Comparison with geranylated flavonoids, mimulone and diplacone. Biochem Pharmacol. 2019 Nov;169:113609. [Content Brief]

[3]. Puopolo T, et al. Gram-Scale Preparation of Cannflavin A from Hemp (Cannabis sativa L.) and Its Inhibitory Effect on Tryptophan Catabolism Enzyme Kynurenine-3-Monooxygenase. Biology (Basel). 2022 Sep 28;11(10):1416. [Content Brief]

[4]. Tomko AM, et al. Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer. J Cannabis Res. 2022 Jul 22;4(1):41. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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