Carbonic anhydrase inhibitor 10
Carbonic anhydrase inhibitor 10 is a potent hCA IX inhibitor with a Ki value of 6.2 nM. Carbonic anhydrase inhibitor 10 exhibits anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 μM. Carbonic anhydrase inhibitor 10 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2883453-30-1
- Formula: C14H17N5O3S
- Molecular Weight:335.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CA IX |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
11.92 μM
Compound: 6c
|
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition measured for 72 hrs by MTT assay
|
[PMID: 34871842] |
Chemical Information
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CAS No. 2883453-30-1
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Molecular Weight 335.38
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Formula C14H17N5O3S
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SMILES
CC1=NC(C)=C(N=C1NC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)