107438-79-9
107438-79-9
Chemical Structure
Ginkgolide J
- CAS No.: 107438-79-9
- Formula:C20H24O10
- Molecular Weight:424.40
InChIKey: LMEHVEUFNRJAAV-UJUBRRQFSA-N
SMILES: O[C@@]1([C@@H]2C)C3(O[C@@](OC4=O)([H])C5([C@H]4O)[C@H](C(C)(C)C)[C@@H](O)[C@@]6([H])OC3=O)[C@@]56C[C@]1([H])OC2=O
Biological Activity: Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability[1][2].
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Ginkgolide J | 99.79% | Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 µM, has neuroprotective and anti neuronal apoptotic ability. | ||||||||||||||||||||
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Ginkgolide J (Standard) | ≥98% | Ginkgolide J (Standard) is the analytical standard of Ginkgolide J. This product is intended for research and analytical applications. Ginkgolide J is a main constituent of the non-flavone fraction of Ginkgo biloba with an IC50 range of 12-54 μM, has neuroprotective and anti neuronal apoptotic ability. | ||||||||||||||||||||
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References
- [1]. Ahlemeyer B, et al. Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease. Pharmacopsychiatry. 2003 Jun; 36 Suppl 1:S8-14. [Content Brief]
- [2]. Sylvia Pietri, et al. Synthesis and Biological Studies of a New Ginkgolide C Derivative: Evidence That the Cardioprotective Effect of Ginkgolides Is Unrelated to PAF Inhibition. DRUG DEVELOPMENT RESEARCH. 2001.54:191-201.
