112-39-0
Chemical Structure
Methyl palmitate
- CAS No.: 112-39-0
- Formula:C17H34O2
- Molecular Weight:270.45
IUPAC Name: methyl palmitate
InChIKey: FLIACVVOZYBSBS-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCC(OC)=O
Biological Activity: Methyl palmitate is a naturally occurring fatty acid ester. Methyl palmitate is a potent inhibitor of ΙκB phosphorylation. Methyl palmitate modulates macrophage activity and down-regulates pro-inflammatory mediators such as TNF-α and nitric oxide (NO). Methyl palmitate possesses anti-inflammatory and antifibrotic effects. Methyl palmitate can inhibit LPS (HY-D1056)-induced Kupffer cells and rat peritoneal macrophages. Methyl palmitate is able to inhibit the phagocytic function of RAW cells. Methyl palmitate is antagonistic to muscarinic receptors. Methyl palmitate exerts cardioprotective effects against ischemia/reperfusion injury in vivo. Methyl palmitate is highly toxic against adult T. cinnabarinus[1][2][3][4][5].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Methyl palmitate | 98.60% | Methyl palmitate is a naturally occurring fatty acid ester. Methyl palmitate is a potent inhibitor of ΙκB phosphorylation. Methyl palmitate modulates macrophage activity and down-regulates pro-inflammatory mediators such as TNF-α and nitric oxide (NO). Methyl palmitate possesses anti-inflammatory and antifibrotic effects. Methyl palmitate can inhibit LPS (HY-D1056)-induced Kupffer cells and rat peritoneal macrophages. Methyl palmitate is able to inhibit the phagocytic function of RAW cells. Methyl palmitate is antagonistic to muscarinic receptors. Methyl palmitate exerts cardioprotective effects against ischemia/reperfusion injury in vivo. Methyl palmitate is highly toxic against adult T. cinnabarinus. | ||||||||||||||||||||
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Methyl palmitate (Standard) | ≥98% | Methyl palmitate (Standard) is the analytical standard of Methyl palmitate. This product is intended for research and analytical applications. Methyl palmitate, an acaricidal compound occurring in Lantana camara, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects. | ||||||||||||||||||||
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Methyl palmitate-d31 | 99.11% | Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects. | ||||||||||||||||||||
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Methyl palmitate-13C16 | 99.80% | Methyl palmitate-13C16 is the 13C labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects. | ||||||||||||||||||||
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Methyl stearate | 99.31% | Methyl stearate, isolated from Rheum palmatum L. is a compopent of of soybean and rapeseed biodiesels. | ||||||||||||||||||||
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Ethyl palmitate (Standard) | 98.98% | Ethyl palmitate (Standard) is the analytical standard of Ethyl palmitate. This product is intended for research and analytical applications. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent. | ||||||||||||||||||||
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Methyl nonadecanoate | 98.54% | Methyl nonadecanoate is an internal standard. Methyl nonadecanoate can be used to determine the content of fatty acid methyl esters (FAME) in biodiesel. | ||||||||||||||||||||
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Methyl tridecanoate (Standard) | ≥98% | Methyl tridecanoate (Standard) is the analytical standard of Methyl tridecanoate. This product is intended for research and analytical applications. Methyl tridecanoate moderately inhibits β-amyloid aggregation. Methyl tridecanoate weakly inhibits acetylcholinesterase (AChE). | ||||||||||||||||||||
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Methyl myristate (Standard) | 99.68% | Methyl myristate (Standard) is the analytical standard of Methyl myristate. This product is intended for research and analytical applications. Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma. | ||||||||||||||||||||
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Methyl pentadecanoate | 99.51% | Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol. | ||||||||||||||||||||
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Methyl heptadecanoate | 99.69% | Methyl heptadecanoate (Methyl margarate) is a methyl ester derivative of heptadecanoic acid (HY-W004284). Methyl heptadecanoate is used as an internal standard for the quantitative calibration of fatty acids in GC-MS analysis. | ||||||||||||||||||||
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Methyl arachidate | 98.0% | Methyl arachidate (Methyl icosanoate) is a component of lipid mixtures. Methyl arachidate can be isolated from flowering plants. Methyl arachidate inhibits LTA4H. Methyl arachidate shows no antifeedant activity against Leptinotarsa decemlineata. | ||||||||||||||||||||
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Methyl 15-bromopentadecanoate | Methyl 15-bromopentadecanoate is a PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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Methyl 15-hydroxypentadecanoate | Methyl 15-hydroxypentadecanoate (Pentadecanoic acid,15-hydroxy-,methyl ester) is an ester product. | |||||||||||||||||||||
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References
- [1]. El-Demerdash E, et al, Anti-inflammatory and antifibrotic effects of methyl palmitate. Toxicol Appl Pharmacol. 2011 Aug 1;254(3):238-44. [Content Brief]
- [2]. N. R. Di Luzio, et al. Depression of phagocytic activity and immune response by methyl palmitate. Am J Physiol. 1964 May;206:939-43. [Content Brief]
- [3]. Y. N. Wang, et al. Methyl Palmitate, an Acaricidal Compound Occurring in Green Walnut Husks. Journal of Economic Entomology, Volume 102, Issue 1, 1 February 2009, Pages 196–202.
- [4]. Saeed, N. M., et al., (2012). Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. Toxicology and applied pharmacology, 264(1), 84–93. [Content Brief]
- [5]. Shen, Y. J., et al., (2021). Methyl palmitate protects heart against ischemia/reperfusion-induced injury through G-protein coupled receptor 40-mediated activation of the PI3K/AKT pathway. European journal of pharmacology, 905, 174183. [Content Brief]