112-39-0
Chemical Structure
Methyl palmitate
- CAS No.: 112-39-0
- Formula:C17H34O2
- Molecular Weight:270.45
IUPAC Name: methyl palmitate
InChIKey: FLIACVVOZYBSBS-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCC(OC)=O
Biological Activity: Methyl palmitate is a naturally occurring fatty acid ester. Methyl palmitate is a potent inhibitor of ΙκB phosphorylation. Methyl palmitate modulates macrophage activity and down-regulates pro-inflammatory mediators such as TNF-α and nitric oxide (NO). Methyl palmitate possesses anti-inflammatory and antifibrotic effects. Methyl palmitate can inhibit LPS (HY-D1056)-induced Kupffer cells and rat peritoneal macrophages. Methyl palmitate is able to inhibit the phagocytic function of RAW cells. Methyl palmitate is antagonistic to muscarinic receptors. Methyl palmitate exerts cardioprotective effects against ischemia/reperfusion injury in vivo. Methyl palmitate is highly toxic against adult T. cinnabarinus[1][2][3][4][5].
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Methyl palmitate | 98.60% | Methyl palmitate is a naturally occurring fatty acid ester. Methyl palmitate is a potent inhibitor of ΙκB phosphorylation. Methyl palmitate modulates macrophage activity and down-regulates pro-inflammatory mediators such as TNF-α and nitric oxide (NO). Methyl palmitate possesses anti-inflammatory and antifibrotic effects. Methyl palmitate can inhibit LPS (HY-D1056)-induced Kupffer cells and rat peritoneal macrophages. Methyl palmitate is able to inhibit the phagocytic function of RAW cells. Methyl palmitate is antagonistic to muscarinic receptors. Methyl palmitate exerts cardioprotective effects against ischemia/reperfusion injury in vivo. Methyl palmitate is highly toxic against adult T. cinnabarinus. | ||||||||||||||||||||
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Methyl palmitate (Standard) | ≥98% | Methyl palmitate (Standard) is the analytical standard of Methyl palmitate. This product is intended for research and analytical applications. Methyl palmitate, an acaricidal compound occurring in Lantana camara, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects. | ||||||||||||||||||||
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Methyl palmitate-d31 | 99.11% | Methyl palmitate-d31 is the deuterium labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects. | ||||||||||||||||||||
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Methyl palmitate-13C16 | 99.80% | Methyl palmitate-13C16 is the 13C labeled Methyl palmitate. Methyl palmitate, an acaricidal compound occurring in green walnut husks, inhibits phagocytic activity and immune response. Methyl palmitate also posseses anti-inflammatory and antifibrotic effects. | ||||||||||||||||||||
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Similarity Score 0.97
HY-W004290Methyl heptadecanoate -
Similarity Score 0.97
HY-W004289Methyl pentadecanoate -
Similarity Score 0.95
HY-B1934Methyl stearate -
Similarity Score 0.94
HY-W004288RMethyl myristate (Standard) -
Similarity Score 0.93
HY-W004262Methyl nonadecanoate -
Similarity Score 0.92
HY-W286101Methyl 15-hydroxypentadecanoate -
Similarity Score 0.91
HY-W004287RMethyl tridecanoate (Standard) -
Similarity Score 0.91
HY-N2086REthyl palmitate (Standard) -
Similarity Score 0.91
HY-W088469Methyl 15-bromopentadecanoate -
Explore the MedChemAI to find more analogs
References
- [1]. El-Demerdash E, et al, Anti-inflammatory and antifibrotic effects of methyl palmitate. Toxicol Appl Pharmacol. 2011 Aug 1;254(3):238-44. [Content Brief]
- [2]. N. R. Di Luzio, et al. Depression of phagocytic activity and immune response by methyl palmitate. Am J Physiol. 1964 May;206:939-43. [Content Brief]
- [3]. Y. N. Wang, et al. Methyl Palmitate, an Acaricidal Compound Occurring in Green Walnut Husks. Journal of Economic Entomology, Volume 102, Issue 1, 1 February 2009, Pages 196–202.
- [4]. Saeed, N. M., et al., (2012). Anti-inflammatory activity of methyl palmitate and ethyl palmitate in different experimental rat models. Toxicology and applied pharmacology, 264(1), 84–93. [Content Brief]
- [5]. Shen, Y. J., et al., (2021). Methyl palmitate protects heart against ischemia/reperfusion-induced injury through G-protein coupled receptor 40-mediated activation of the PI3K/AKT pathway. European journal of pharmacology, 905, 174183. [Content Brief]
