112-84-5
112-84-5
Chemical Structure
Erucamide
Synonym(s): cis-13-Docosenamide
- CAS No.: 112-84-5
- Formula:C22H43NO
- Molecular Weight:337.58
IUPAC Name: (Z)-docos-13-enamide
InChIKey: UAUDZVJPLUQNMU-KTKRTIGZSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCCCCCC(N)=O
Biological Activity: Erucamide is an orally active, blood-brain barrier-permeable TMEM19 ligand and T3SS inhibitor. Erucamide exerts retinal neuroprotective effects in mouse models of retinal degeneration. Erucamide attenuates depression- and anxiety-like behaviors in mice.\n\nErucamide binds to the conserved hydrophobic pocket in HrcC, disrupts its outer membrane localization, and blocks T3SS-mediated effector protein secretion in Gram-negative pathogenic bacteria. Erucamide enhances the antimicrobial immunity of plants against pathogenic bacteria. Erucamide can be used in research related to retinitis pigmentosa, anxiety and depression, bacterial wilt, and bacterial blight[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Erucamide | 99.35% | Erucamide is an orally active, blood-brain barrier-permeable TMEM19 ligand and T3SS inhibitor. Erucamide exerts retinal neuroprotective effects in mouse models of retinal degeneration. Erucamide attenuates depression- and anxiety-like behaviors in mice.\n\nErucamide binds to the conserved hydrophobic pocket in HrcC, disrupts its outer membrane localization, and blocks T3SS-mediated effector protein secretion in Gram-negative pathogenic bacteria. Erucamide enhances the antimicrobial immunity of plants against pathogenic bacteria. Erucamide can be used in research related to retinitis pigmentosa, anxiety and depression, bacterial wilt, and bacterial blight. | ||||||||||||||||||||
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Erucamide (Standard) | ≥98% | Erucamide (Standard) is the analytical standard of Erucamide. This product is intended for research and analytical applications. Erucamide inhibits intestinal diarrhea.Erucamide also regulates the volume of body fluids in other organs. Erucamide has the ability to promote angiogenesis. | ||||||||||||||||||||
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Cetoleic acid | 99.99% | Cetoleic acid is a long-chain monounsaturated fatty acid found in deep-sea fish. Cetoleic acid can promote the synthesis of ALA in human HepG2 cells and EPA in vitro in salmon liver cells, affecting cholesterol levels in rodents. Cetoleic acid has potential applications in cardiovascular disease research. | ||||||||||||||||||||
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13(E)-Docosenoic acid (Standard) | ≥98% | 2,4-D methyl ester (Standard) is the analytical standard of 2,4-D methyl ester. This product is intended for research and analytical applications. 2,4-D methyl ester is a bioactive compound with the activity of promoting the accumulation of nutritional and medicinal components. 2,4-D methyl ester can be used to enhance the production of bioactive components in Cordyceps militaris. 2,4-D methyl ester showed an inductive effect on bioactive components at specific concentrations. The application of 2,4-D methyl ester provides an effective strategy to improve the fruit quality of Cordyceps militaris. 2,4-D methyl ester, as a biostimulant, can induce dose-dependent responses in different components. | ||||||||||||||||||||
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13(E)-Docosenoyl chloride | 13(E)-Docosenoyl chloride is an ester product. | |||||||||||||||||||||
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13(Z)-Docosenoyl chloride | 13(Z)-Docosenoyl chloride (Erucic acid chloride; (13Z)-13-Docosenoyl chloride) is an ester product. | |||||||||||||||||||||
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14(Z)-Tricosenoyl chloride | 14(Z)-Tricosenoyl chloride is an ester product. | |||||||||||||||||||||
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cis-12-Heneicosenoic acid | cis-12-Heneicosenoic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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Oleamide | 99.96% | Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma. | ||||||||||||||||||||
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9(E)-Octadecenamide | 9(E)-Octadecenamide (Elaidic acid amide) is an ester product. | |||||||||||||||||||||
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Erucic acid (Standard) | 99.78% | Erucic acid (Standard) is the analytical standard of Erucic acid. This product is intended for research and analytical applications. Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia. | ||||||||||||||||||||
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(E/Z)-Oleamide | 99.97% | (E/Z)-Oleamide (Octadec-9-enamide) is a PPARα ligand in hippocampal nuclei. (E/Z)-Oleamide can be isolated from plant Galium aparine L. (GA). (E/Z)-Oleamide controls hippocampal plasticity via transcriptional activation of CREB, and regulates feeding and sexual behavior in rats. | ||||||||||||||||||||
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References
- [1]. Hamberger A, et al. Erucamide as a modulator of water balance: new function of a fatty acid amide. Neurochem Res.2003 Feb;28(2):177-85. [Content Brief]
- [2]. Li MM, et al. Antidepressant and anxiolytic-like behavioral effects of erucamide, a bioactive fatty acid amide, involving the hypothalamus-pituitary-adrenal axis in mice. Neurosci Lett. 2017 Feb 15;640:6-12. [Content Brief]
- [3]. Wei G, et al. Erucamide regulates retinal neurovascular crosstalk. bioRxiv [Preprint]. 2025 Sep 7:2025.09.02.673793. [Content Brief]
- [4]. Miao P, et al. A widespread plant defense compound disarms bacterial type III injectisome assembly. Science. 2025;387(6737):eads0377. [Content Brief]
